RNA Details
Disease Name
endomyocardial fibrosis
Tissue
heart
RNA Symbol
mir-214
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
mus musculus
Detection Methods
PCR; immunofluorescence etc.
Target
EZH1;EZH2
Pathway
NF-KAPPA B SIGNALING PATHWAY
PubMed ID
Title
Targeting EZH1 and EZH2 contributes to the suppression of fibrosis-associated genes by miR-214-3p in cardiac myofibroblasts
Year
2016
Function
"Ezh1 was novel targets of miR-214-3p,miR-214-3p inhibited the expression of Col1a1 and Col3a1 in mouse myofibroblasts and miR-214-3p might be one potential miRNA for the prevention of cardiac fibrosis."